Catecholamine Uptake, Accumulation, and Release in Acute Porphyria
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چکیده
منابع مشابه
Catecholamine uptake, storage, and regulated release by ovarian granulosa cells.
Catecholamines present in the mammalian ovary are involved in many normal aspects of ovarian functions, including initial follicle growth, steroidogenesis, and pathological states such as polycystic ovary syndrome. Sympathetic nerve fibers are the largest source of norepinephrine (NE), but not the only one. Surgical denervation of the rat ovary reduces, but does not eliminate, the ovarian conte...
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PORPHYRIA is a rare disorder of metabolism, in which there is increased production and excretion of uroporphyrin, coproporphyrin, and porphobilinogen.' Despite recent reviews (Goldman and Kaplan (1951), Watson (1951), and Janoff, Poutas, and Young (1953) ), the disease is unfamiliar, but recently there have been an increasing number of case reports. Acute porphyria may present such varied sympt...
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abstract most pheochromocytomas are not suspected clinically while a high percentage of them are curable with surgery. we present the case of an adult cocaine-addicted male patient with an underlying pheochromocytoma and repeated myocardial infarctions. computed tomography showed a left round adrenal mass, also high 24-hour urine levels of catecholamines and metanephrines were detected from uri...
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The porphyrias comprise a set of diseases, each representing an individual defect in one of the eight enzymes mediating the pathway of heme synthesis. The diseases are genetically distinct but have in common the overproduction of heme precursors. In the case of the acute (neurologic) porphyrias, the cause of symptoms appears to be overproduction of a neurotoxic precursor. For the cutaneous porp...
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Acute intermittent porphyria (AIP) is an autosomal dominant genetic defect in heme synthesis. Patients with this illness can have episodic life-threatening attacks characterized by abdominal pain, neurological deficits, and psychiatric symptoms. Feigning this illness has not been reported in the English language literature to date. Here, we report on a patient who presented to the hospital with...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1977
ISSN: 0021-9738
DOI: 10.1172/jci108866